3D optical/CT as a preclinical companion imaging platform for glioblastoma drug development

• Main Authors: Andrei Molotkov (Author), Mikhail Doubrovin (Author), Nikunj Bhatt (Author), Fang-Chi Hsu (Author), Amanda Beserra (Author), Rajiv Chopra (Author), Akiva Mintz (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multimodality 3D Optical Imaging (OI)/CT has the potential to play a major role in drug development for glioblastomas (GBM), as it is an accessible preclinical method. To demonstrate the potential of 3D OI/CT to visualize orthotopic GBM implantation, we labeled GBM cells with Cy7 and imaged their lo...