Regulation of Hypoxic-Adenosinergic Signaling by Estrogen: Implications for Microvascular Injury

• मुख्य लेखकों: Jessica Cassavaugh (लेखक), Nada Qureshi (लेखक), Eva Csizmadia (लेखक), Maria Serena Longhi (लेखक), Robina Matyal (लेखक), Simon C. Robson (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Loss of estrogen, as occurs with normal aging, leads to increased inflammation, pathologic angiogenesis, impaired mitochondrial function, and microvascular disease. While the influence of estrogens on purinergic pathways is largely unknown, extracellular adenosine, generated at high levels by CD39 a...