Case Report: Ophthalmologic Evaluation Over a Long Follow-Up Time in a Patient With Wolfram Syndrome Type 2: Slowly Progressive Optic Neuropathy as a Possible Clinical Finding

• Main Authors: Valentina Di Iorio (Author), Enza Mozzillo (Author), Francesco Maria Rosanio (Author), Francesca Di Candia (Author), Rita Genesio (Author), Francesco Testa (Author), Claudio Iovino (Author), Adriana Franzese (Author), Francesca Simonelli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Wolfram syndrome (WFS) is a rare autosomal recessive neurodegenerative disease whose diagnosis requires diabetes mellitus and optic atrophy (OA). WFS includes a wide spectrum of other possible complications such as diabetes insipidus, sensorineural deafness, urinary tract problems, neurological and...