Neural and molecular investigation into the paraventricular thalamic-nucleus accumbens circuit for pain sensation and non-opioid analgesia

• Main Authors: Guangchao Zhang (Author), Mengqiao Cui (Author), Ran Ji (Author), Shiya Zou (Author), Lingzhen Song (Author), Bingqian Fan (Author), Li Yang (Author), Di Wang (Author), Suwan Hu (Author), Xiao Zhang (Author), Tantan Fang (Author), Xiaolu Yu (Author), Jun-Xia Yang (Author), Dipesh Chaudhury (Author), He Liu (Author), Ankang Hu (Author), Hai-Lei Ding (Author), Jun-Li Cao (Author), Hongxing Zhang (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The paucity of medications with novel mechanisms for pain treatment combined with the severe adverse effects of opioid analgesics has led to an imperative pursuit of non-opioid analgesia and a better understanding of pain mechanisms. Here, we identify the putative glutamatergic inputs from the parav...