Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis.

• Main Authors: Jean Rodgers (Author), Amy Jones (Author), Stéphane Gibaud (Author), Barbara Bradley (Author), Christopher McCabe (Author), Michael P Barrett (Author), George Gettinby (Author), Peter G E Kennedy (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites Trypanosoma brucei (T. b.) gambiense or T. b. rhodesiense and is invariably fatal if untreated. There are 60 million people at risk from the disease throughout sub-Saharan Africa. The infec...