GdCl3 attenuates the glomerular sclerosis of streptozotocin (STZ) induced diabetic rats via inhibiting TGF-β/Smads signal pathway

• Main Authors: Jialin Li (Author), Bing Wu (Author), Haibo Hu (Author), Xiansong Fang (Author), Zhiping Liu (Author), Suzhen Wu (Author)
• Format: Knjiga
• Izdano: Elsevier, 2020-02-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Diabetic nephropathy (DN) is the most serious end-stage renal disease which characterized by renal glomerular sclerosis including glomerular hypertrophy, glomerular basement membrane (GBM) thickening, mesangial expansion and renal fibrosis. TGF-β/Smads signal pathway plays a crucial role in the deve...