Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects

• Main Authors: Heewon Seo (Author), Eun Jin Kwon (Author), Young-Ah You (Author), Yoomi Park (Author), Byung Joo Min (Author), Kyunghun Yoo (Author), Han-Sung Hwang (Author), Ju Han Kim (Author), Young Ju Kim (Author)
• Format: Book
• Published: BMC, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ritodrine is a commonly used tocolytic to prevent preterm labour. However, it can cause unexpected serious adverse reactions, such as pulmonary oedema, pulmonary congestion, and tachycardia. It is unknown whether such adverse reactions are associated with pharmacogenomic variants...