EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene

EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene

We recently demonstrated tumor-selective iodide uptake and therapeutic efficacy of combined radiovirotherapy after systemic delivery of the theranostic sodium iodide symporter (NIS) gene using a dendrimer-coated adenovirus. To further improve shielding and targeting we physically coated replication-...

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Main Authors: Geoffrey K Grünwald (Author), Alexandra Vetter (Author), Kathrin Klutz (Author), Michael J Willhauck (Author), Nathalie Schwenk (Author), Reingard Senekowitsch-Schmidtke (Author), Markus Schwaiger (Author), Christian Zach (Author), Ernst Wagner (Author), Burkhard Göke (Author), Per S Holm (Author), Manfred Ogris (Author), Christine Spitzweg (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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3rd Floor Main Library

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