Phenotypic evidence of emerging ivermectin resistance in Onchocerca volvulus.

• Main Authors: Mike Y Osei-Atweneboana (Author), Kwablah Awadzi (Author), Simon K Attah (Author), Daniel A Boakye (Author), John O Gyapong (Author), Roger K Prichard (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ivermectin (IVM) has been used in Ghana for over two decades for onchocerciasis control. In recent years there have been reports of persistent microfilaridermias despite multiple treatments. This has necessitated a reexamination of its microfilaricidal and suppressive effects on reproduction in the...