Increase in TGF-β secreting CD4⁺CD25⁺ FOXP3⁺ T regulatory cells in anergic lepromatous leprosy patients.

BACKGROUND: Lepromatous leprosy caused by Mycobacterium leprae is associated with antigen specific T cell unresponsiveness/anergy whose underlying mechanisms are not fully defined. We investigated the role of CD25(+)FOXP3(+) regulatory T cells in both skin lesions and M.leprae stimulated PBMC cultur...

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Main Authors: Chaman Saini (Author), Venkatesh Ramesh (Author), Indira Nath (Author)
Format: Book
Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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