Estimation of plasma and RBC acetylcholinesterase in children: An evaluation tool for Hirschsprung's disease?

• Main Authors: Neha Kuvelkar (Author), Serena DSouza (Author), K Vidhyashree (Author), Gowri Shankar (Author), Maria Frances Bukel (Author), Santosh Noronha (Author), Usha Kini (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Increased acetylcholinesterase (AChE) activity on frozen sections of rectal mucosal biopsies accurately diagnoses Hirschsprung disease (HD). But the quest for a biomarker in blood as a screening test prompts one to look for AChE in blood and study its role in HD diagnosis. Aim: To develo...