Pathogen and host factors are needed to provoke a systemic host response to gastrointestinal infection of Drosophila larvae by Candida albicans

• Main Authors: Marcus T. Glittenberg (Author), Ilias Kounatidis (Author), David Christensen (Author), Magali Kostov (Author), Sandra Kimber (Author), Ian Roberts (Author), Petros Ligoxygakis (Author)
• Format: Book
• Published: The Company of Biologists, 2011-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY Candida albicans systemic dissemination in immunocompromised patients is thought to develop from initial gastrointestinal (GI) colonisation. It is unclear what components of the innate immune system are necessary for preventing C. albicans dissemination from the GI tract, but studies in mice...