mTOR Modulates the Endoplasmic Reticulum Stress-Induced CD4+ T Cell Apoptosis Mediated by ROS in Septic Immunosuppression

• Ngā kaituhi matua: Hao Wang (Author), Jianwei Chen (Author), Guangxu Bai (Author), Wen Han (Author), Ran Guo (Author), Na Cui (Author)
• Hōputu: Pukapuka
• I whakaputaina: Hindawi Limited, 2022-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Introduction. When sepsis attacks the body, the excessive reactive oxygen species (ROS) production can result to endoplasmic reticulum stress (ERS) and eventually cause lymphocyte apoptosis. The mammalian target of rapamycin (mTOR) is essential for regulating lymphocyte apoptosis; we hypothesized th...