Inhibiting collagen I production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles

• Main Authors: Yan Yan (Author), Cancan Du (Author), Xixi Duan (Author), Xiaohan Yao (Author), Jiajia Wan (Author), Ziming Jiang (Author), Zhongyu Qin (Author), Wenqing Li (Author), Longze Pan (Author), Zhuoyu Gu (Author), Fazhan Wang (Author), Ming Wang (Author), Zhihai Qin (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The lung is one of the most common sites for cancer metastasis. Collagens in the lung provide a permissive microenvironment that supports the colonization and outgrowth of disseminated tumor cells. Therefore, down-regulating the production of collagens may contribute to the inhibition of lung metast...