ATF3 promotes ferroptosis in sorafenib-induced cardiotoxicity by suppressing Slc7a11 expression

Sorafenib is the unique recommended molecular-targeted drug for advanced hepatocellular carcinoma, but its clinical use is limited due to cardiotoxicity. As sorafenib is an efficient ferroptosis inducer, the pathogenesis of this compound to ferroptosis-mediated cardiotoxicity is worth further study....

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Main Authors: Yilan Li (Author), Jingru Yan (Author), Qianqian Zhao (Author), Yan Zhang (Author), Yao Zhang (Author)
Format: Book
Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
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