GSH-sensitive polymeric prodrug: Synthesis and loading with photosensitizers as nanoscale chemo-photodynamic anti-cancer nanomedicine

• Main Authors: Lei Luo (Author), Yiming Qi (Author), Hong Zhong (Author), Shinan Jiang (Author), Hu Zhang (Author), Hao Cai (Author), Yahui Wu (Author), Zhongwei Gu (Author), Qiyong Gong (Author), Kui Luo (Author)
• Format: Book
• Published: Elsevier, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Precisely delivering combinational therapeutic agents has become a crucial challenge for anti-tumor treatment. In this study, a novel redox-responsive polymeric prodrug (molecular weight, MW: 93.5 kDa) was produced by reversible addition-fragmentation chain transfer (RAFT) polymerization. The amphip...