Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

• Main Authors: Erica L. Bradshaw (Author), Mary E. Spilker (Author), Richard Zang (Author), Loveleena Bansal (Author), Handan He (Author), Rhys D.O. Jones (Author), Kha Le (Author), Mark Penney (Author), Edgar Schuck (Author), Brian Topp (Author), Alice Tsai (Author), Christine Xu (Author), Marjoleen J.M.A. Nijsen (Author), Jason R. Chan (Author)
• Format: Book
• Published: Wiley, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Quantitative systems pharmacology (QSP) approaches have been increasingly applied in the pharmaceutical since the landmark white paper published in 2011 by a National Institutes of Health working group brought attention to the discipline. In this perspective, we discuss QSP in the context o...