Soluble CD14 Enhances the Response of Periodontal Ligament Stem Cells to Toll-Like Receptor 2 Agonists

• Egile Nagusiak: Christian Behm (Egilea), Alice Blufstein (Egilea), Johannes Gahn (Egilea), Nazanin Noroozkhan (Egilea), Andreas Moritz (Egilea), Xiaohui Rausch-Fan (Egilea), Oleh Andrukhov (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2019-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Human periodontal ligament stem cells (hPDLSCs) do not express membrane-bound CD14, and their responsiveness to bacterial lipopolysaccharide (LPS) is drastically enhanced by soluble CD14 (sCD14), which is due to the facilitation of the interaction between LPS and Toll-like receptor- (TLR-) 4. Severa...