Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism

• Main Authors: Ying Tan (Author), Yue Zhang (Author), Jing He (Author), Feng Wu (Author), Di Wu (Author), Nengxian Shi (Author), Weifeng Liu (Author), Ziying Li (Author), Wenqian Liu (Author), Hao Zhou (Author), Wenting Chen (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Dual specificity phosphatase 1 (DUSP1) is regarded as an anti-inflammatory factor in cardiovascular disorders. Mitophagy removes damaged mitochondria and thus promotes mitochondrial regeneration. We investigated whether DUSP1 could attenuate inflammation-induced cardiomyopathy by improvi...