Ketogal Safety Profile in Human Primary Colonic Epithelial Cells and in Mice

• मुख्य लेखकों: Federica Sodano (लेखक), Bice Avallone (लेखक), Monica Tizzano (लेखक), Chiara Fogliano (लेखक), Barbara Rolando (लेखक), Elena Gazzano (लेखक), Chiara Riganti (लेखक), Salvatore Magliocca (लेखक), Mariarosaria Cuozzo (लेखक), Stefania Albrizio (लेखक), Antonio Calignano (लेखक), Claudia Cristiano (लेखक), Roberto Russo (लेखक), Maria Grazia Rimoli (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

In our previous studies, a ketorolac-galactose conjugate (ketogal) showed prolonged anti-inflammatory and analgesic activity, causing less gastric ulcerogenic effect and renal toxicity than its parent drug ketorolac. In order to demonstrate the safer profile of ketogal compared to ketorolac, histopa...