Chitosan Oleate Coated PLGA Nanoparticles as siRNA Drug Delivery System

• Main Authors: Dalila Miele (Author), Xin Xia (Author), Laura Catenacci (Author), Milena Sorrenti (Author), Silvia Rossi (Author), Giuseppina Sandri (Author), Franca Ferrari (Author), John J. Rossi (Author), Maria Cristina Bonferoni (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oligonucleotide therapeutics such as miRNAs and siRNAs represent a class of molecules developed to modulate gene expression by interfering with ribonucleic acids (RNAs) and protein synthesis. These molecules are characterized by strong instability and easy degradation due to nuclease enzymes. To avo...