Design, Synthesis and In Vitro Investigation of Cabozantinib-Based PROTACs to Target c-Met Kinase
(1) Background: This investigation aimed at developing a series of c-Met-targeting cabozantinib-based PROTACs. (2) Methods: Purification of intermediate and target compounds was performed using column chromatography, in vitro antiproliferation activity was measured using a standard MTT assay and a c...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2022-12-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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