Utilization of Polymeric Micelles as a Lucrative Platform for Efficient Brain Deposition of Olanzapine as an Antischizophrenic Drug via Intranasal Delivery
Schizophrenia is a mental disorder characterized by alterations in cognition, behavior and emotions. Oral olanzapine (OZ) administration is extensively metabolized (~up to 40% of the administrated dose). In addition, OZ is a P-glycoproteins substrate that impairs the blood-brain barrier (BBB) permea...
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Main Authors: | Hadel A. Abo El-Enin (Author), Marwa F. Ahmed (Author), Ibrahim A. Naguib (Author), Shaymaa W. El-Far (Author), Mohammed M. Ghoneim (Author), Izzeddin Alsalahat (Author), Hend Mohamed Abdel-Bar (Author) |
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Format: | Book |
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MDPI AG,
2022-02-01T00:00:00Z.
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