A novel fatty acid mimetic with pan-PPAR partial agonist activity inhibits diet-induced obesity and metabolic dysfunction-associated steatotic liver disease

• Main Authors: Cigdem Sahin (Author), Jenna-Rose Melanson (Author), Florian Le Billan (Author), Lilia Magomedova (Author), Thais A.M. Ferreira (Author), Andressa S. Oliveira (Author), Evan Pollock-Tahari (Author), Michael F. Saikali (Author), Sarah B. Cash (Author), Minna Woo (Author), Luiz A.S. Romeiro (Author), Carolyn L. Cummins (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The prevalence of metabolic diseases is increasing globally at an alarming rate; thus, it is essential that effective, accessible, low-cost therapeutics are developed. Peroxisome proliferator-activated receptors (PPARs) are transcription factors that tightly regulate glucose homeostasis a...