Drug Discovery Models and Toxicity Testing Using Embryonic and Induced Pluripotent Stem-Cell-Derived Cardiac and Neuronal Cells

• Hauptverfasser: Rahul S. Deshmukh (Verfasst von), Krisztián A Kovács (Verfasst von), András Dinnyés (Verfasst von)
• Format: Buch
• Veröffentlicht: Hindawi Limited, 2012-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Development of induced pluripotent stem cells (iPSCs) using forced expression of specific sets of transcription factors has changed the field of stem cell research extensively. Two important limitations for research application of embryonic stem cells (ESCs), namely, ethical and immunological issues...