MicroRNA-125b Promotes Hepatic Stellate Cell Activation and Liver Fibrosis by Activating RhoA Signaling

• Main Authors: Kai You (Author), Song-Yang Li (Author), Jiao Gong (Author), Jian-Hong Fang (Author), Chong Zhang (Author), Min Zhang (Author), Yunfei Yuan (Author), Jine Yang (Author), Shi-Mei Zhuang (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

miR-125b is frequently dysregulated in different diseases. Activation of hepatic stellate cells (HSCs) is a critical event during liver fibrogenesis. However, the function and its underlying mechanism of miR-125b in HSC activation and liver fibrosis are still unknown. Here, we showed that miR-125b w...