Protective Efficacy of Inhaled BCG Vaccination Against Ultra-Low Dose Aerosol <i>M. tuberculosis</i> Challenge in Rhesus Macaques

• Main Authors: Andrew D. White (Author), Charlotte Sarfas (Author), Laura S. Sibley (Author), Jennie Gullick (Author), Simon Clark (Author), Emma Rayner (Author), Fergus Gleeson (Author), Martí Català (Author), Isabel Nogueira (Author), Pere-Joan Cardona (Author), Cristina Vilaplana (Author), Mike J. Dennis (Author), Ann Williams (Author), Sally A. Sharpe (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ten million cases of tuberculosis (TB) were reported in 2018 with a further 1.5 million deaths attributed to the disease. Improved vaccination strategies are urgently required to tackle the ongoing global TB epidemic. In the absence of a validated correlate of protection, highly characterised pre-cl...