A temporo-spatial pharmacometabolomics method to characterize pharmacokinetics and pharmacodynamics in the brain microregions by using ambient mass spectrometry imaging

• Váldodahkkit: Dan Liu (Dahkki), Jianpeng Huang (Dahkki), Shanshan Gao (Dahkki), Hongtao Jin (Dahkki), Jiuming He (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2022-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The brain is the most advanced organ with various complex structural and functional microregions. It is often challenging to understand what and where the molecular events would occur for a given drug treatment in the brain. Herein, a temporo-spatial pharmacometabolomics method was proposed based on...