Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARα

• Main Authors: Shihao Xu (Author), Xi Qiao (Author), Peike Peng (Author), Ziyi Zhu (Author), Yaoting Li (Author), Mengyuan Yu (Author), Long Chen (Author), Yin Cai (Author), Jin Xu (Author), Xinwei Shi (Author), Christopher G. Proud (Author), Jianling Xie (Author), Kaikai Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholestasis is caused by intrahepatic retention of excessive toxic bile acids and ultimately results in hepatic failure. Da-Chai-Hu-Tang (DCHT) has been used in China to treat liver and gallbladder diseases for over 1800 years. Here, we demonstrated that DCHT treatment prevented acute intrahepatic c...