Neutrophil as a Carrier for Cancer Nanotherapeutics: A Comparative Study of Liposome, PLGA, and Magnetic Nanoparticles Delivery to Tumors

• Main Authors: Anastasiia S. Garanina (Author), Daniil A. Vishnevskiy (Author), Anastasia A. Chernysheva (Author), Marat P. Valikhov (Author), Julia A. Malinovskaya (Author), Polina A. Lazareva (Author), Alevtina S. Semkina (Author), Maxim A. Abakumov (Author), Victor A. Naumenko (Author)
• Format: Book
• Published: MDPI AG, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Insufficient drug accumulation in tumors is still a major concern for using cancer nanotherapeutics. Here, the neutrophil-based delivery of three nanoparticle types-liposomes, PLGA, and magnetite nanoparticles-was assessed both in vitro and in vivo. Confocal microscopy and a flow cytometry analysis...