Identification of Biologically Active Ganoderma lucidum Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer Activities in vitro

• Main Authors: Michelle M. Martínez-Montemayor (Author), Taotao Ling (Author), Ivette J. Suárez-Arroyo (Author), Gabriela Ortiz-Soto (Author), Camille L. Santiago-Negrón (Author), Mercedes Y. Lacourt-Ventura (Author), Anibal Valentín-Acevedo (Author), Walter H. Lang (Author), Fatima Rivas (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously reported that Ganoderma lucidum extract (GLE) demonstrate significant anti-cancer activity against triple negative inflammatory breast cancer models. Herein, we aimed to elucidate the bioactive compounds of GLE responsible for this anti-cancer activity. We performed NMR, X-ray crystall...