The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells

Jin-Ping Li,1,2 Yin-Xue Yang,3 Qi-Lun Liu,1 Shu-Ting Pan,1,4 Zhi-Xu He,5 Xueji Zhang,6 Tianxin Yang,7 Xiao-Wu Chen,8 Dong Wang,9 Jia-Xuan Qiu,4 Shu-Feng Zhou2,51Department of Surgical Oncology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 2...

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Main Authors: Li JP (Author), Yang YX (Author), Liu QL (Author), Pan ST (Author), He ZX (Author), Zhang X (Author), Yang T (Author), Chen XW (Author), Wang D (Author), Qiu JX (Author), Zhou SF (Author)
Format: Book
Published: Dove Medical Press, 2015-03-01T00:00:00Z.
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