Integrated UPLC-Q/TOF-MS Technique and MALDI-MS to Study of the Efficacy of YiXinshu Capsules Against Heart Failure in a Rat Model

• Main Authors: Jing Xu (Author), Xianyu Li (Author), Fangbo Zhang (Author), Liying Tang (Author), Junying Wei (Author), Xiaoqing Lei (Author), Huanhuan Wang (Author), Yi Zhang (Author), Defeng Li (Author), Xuan Tang (Author), Geng Li (Author), Shihuan Tang (Author), Hongwei Wu (Author), Hongjun Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Yixinshu Capsules (YXSC) are widely used in Chinese medicine for the treatment of cardiovascular diseases. However, the therapeutic mechanisms of action are not well understood.Method: In this study, a metabonomic approach based on integrated UPLC-Q/TOF-MS technique and MALDI-MS was util...