Enhanced amphiregulin exposure promotes modulation of the high grade serous ovarian cancer tumor immune microenvironment

• Main Authors: Jasmine Ebott (Author), Julia McAdams (Author), Chloe Kim (Author), Corrine Jansen (Author), Morgan Woodman (Author), Payton De La Cruz (Author), Christoph Schrol (Author), Jennifer Ribeiro (Author), Nicole James (Author)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

High grade serous ovarian cancer (HGSOC) is a lethal gynecologic malignancy in which chemoresistant recurrence rates remain high. Furthermore, HGSOC patients have demonstrated overall low response rates to clinically available immunotherapies. Amphiregulin (AREG), a low affinity epidermal growth fac...