Tumour‐induced alterations in single‐nucleus transcriptome of atrophying muscles indicate enhanced protein degradation and reduced oxidative metabolism

• Váldodahkkit: Samet Agca (Dahkki), Aylin Domaniku‐Waraich (Dahkki), Sevval Nur Bilgic (Dahkki), Melis Sucuoglu (Dahkki), Meric Dag (Dahkki), Sukru Anil Dogan (Dahkki), Serkan Kir (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2024-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract Background Tumour‐induced skeletal muscle wasting in the context of cancer cachexia is a condition with profound implications for patient survival. The loss of muscle mass is a significant clinical obstacle and is linked to reduced tolerance to chemotherapy and increased frailty. Understand...