Role of T cells during the cerebral infection with Trypanosoma brucei.

• Main Authors: Gabriela C Olivera (Author), Leonie Vetter (Author), Chiara Tesoriero (Author), Federico Del Gallo (Author), Gustav Hedberg (Author), Juan Basile (Author), Martin E Rottenberg (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The infection by Trypanosoma brucei brucei (T.b.b.), a protozoan parasite, is characterized by an early-systemic stage followed by a late stage in which parasites invade the brain parenchyma in a T cell-dependent manner. Here we found that early after infection effector-memory T cells were predomina...