MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation

• Auteurs principaux: Benshuai You (Auteur), Can Jin (Auteur), Jiaxin Zhang (Auteur), Min Xu (Auteur), Wenrong Xu (Auteur), Zixuan Sun (Auteur), Hui Qian (Auteur)
• Format: Livre
• Publié: Hindawi Limited, 2022-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Mesenchymal stem cell- (MSC-) derived extracellular vesicles (EVs) serving as delivery system have attracted extensive research interest, especially in cancer therapy. In our previous study, lipocalin-type prostaglandin D2 synthase (L-PGDS) showed inhibitory effects on gastric cancer growth. In this...