In Vitro Characterization of Reversine-Treated Gingival Fibroblasts and Their Safety Evaluation after In Vivo Transplantation

• Main Authors: Carlos Miguel Marto (Author), Mafalda Laranjo (Author), Ana Cristina Gonçalves (Author), Anabela Paula (Author), Joana Jorge (Author), Rui Caetano-Oliveira (Author), Maria Inês Sousa (Author), Bárbara Oliveiros (Author), João Ramalho-Santos (Author), Ana Bela Sarmento-Ribeiro (Author), Manuel Marques-Ferreira (Author), António Cabrita (Author), Maria Filomena Botelho (Author), Eunice Carrilho (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reversine is a purine derivative that has been investigated with regard to its biological effects, such as its anticancer properties and, mostly, its ability to induce the dedifferentiation of adult cells, increasing their plasticity. The obtained dedifferentiated cells have a high potential for use...