Design, Synthesis and Cytotoxicity Study of Primary Amides as Histone Deacetylase Inhibitors

Primary amide derivatives as histone deacetylase inhibitors (HDACIs) are very rare. This paper describes the synthesis of primary amide derivatives (compounds 6 and 7) that have the requirements to be histone deacetylase inhibitors of the zinc-binding type. Both of them exhibited good cytotoxicity a...

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Bibliographic Details
Main Authors: Duraid Al-Amily (Author), Mohammed H. Mohammed (Author)
Format: Book
Published: College of Pharmacy University of Baghdad, 2019-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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