Design, Synthesis and Cytotoxicity Study of Primary Amides as Histone Deacetylase Inhibitors

Primary amide derivatives as histone deacetylase inhibitors (HDACIs) are very rare. This paper describes the synthesis of primary amide derivatives (compounds 6 and 7) that have the requirements to be histone deacetylase inhibitors of the zinc-binding type. Both of them exhibited good cytotoxicity a...

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Asıl Yazarlar: Duraid Al-Amily (Yazar), Mohammed H. Mohammed (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: College of Pharmacy University of Baghdad, 2019-12-01T00:00:00Z.
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