Discovery of novel and highly potent dual-targeting PKMYT1/HDAC2 inhibitors for hepatocellular carcinoma through structure-based virtual screening and biological evaluation

Simultaneous inhibition of two or more pathways is playing a crucial role in the treatment of hepatocellular carcinoma with complex and diverse pathogenesis. However, there have been no reports of dual-targeting inhibitors for protein kinase membrane-associated tyrosine/threonine 1 (PKMYT1) and hist...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Yang Yang (Autor), Yuting Wang (Autor), Jing Chen (Autor), Miao-Miao Niu (Autor), Yongbin Wang (Autor), Xing Jin (Autor)
Médium: Kniha
Vydáno: Frontiers Media S.A., 2024-11-01T00:00:00Z.
Témata:
On-line přístup:Connect to this object online.
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Internet

Connect to this object online.

3rd Floor Main Library

Informace o exemplářích z: 3rd Floor Main Library
Signatura: A1234.567
Jednotka 1 Dostupné