Interleukin-36 Is Highly Expressed in Skin Biopsies from Two Patients with Netherton Syndrome

• Päätekijät: Johannes Pawlowski (Tekijä), Tatsiana Pukhalskaya (Tekijä), Kelly Cordoro (Tekijä), Marina Kristy Ibraheim (Tekijä), Jeffrey P. North (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2024-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Netherton syndrome (NS) is a rare autosomal recessive disorder that occurs due to a loss-of-function mutation in SPINK5; this loss results in significant inflammation, as well as perturbations of the skin barrier's integrity and functionality. While it is unclear which inflammatory pathways con...