Comparison of the efficacy and safety of leflunomide versus placebo combined with basic prednisone therapy in patients with active disease phase of Takayasu arteritis: study protocol for a randomized, double-blinded controlled trial (Takayasu arteritis clinical trial in China: TACTIC)

• Hoofdauteurs: Ying Sun (Auteur), Bingjie Wu (Auteur), Wei Zhang (Auteur), Lili Ma (Auteur), Xiufang Kong (Auteur), Huiyong Chen (Auteur), Lindi Jiang (Auteur)
• Formaat: Boek
• Gepubliceerd in: SAGE Publishing, 2023-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Background: Takayasu arteritis (TAK) is an immune-induced granulomatous vasculitis that occurs primarily in young Asian women. Our previous cohort studies have indicated that leflunomide (LEF), which can lead to rapid induction and might be a promising alternative treatment for TAK. Objectives: To c...