Stability Study of Parenteral N-Acetylcysteine, and Chemical Inhibition of Its Dimerization

• Autors principals: Nicolas Primas (Autor), Guillaume Lano (Autor), Damien Brun (Autor), Christophe Curti (Autor), Marion Sallée (Autor), Emmanuelle Sampol-Manos (Autor), Edouard Lamy (Autor), Charleric Bornet (Autor), Stéphane Burtey (Autor), Patrice Vanelle (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2023-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Parenteral N-acetylcysteine has a wide variety of clinical applications, but its use can be limited by a poor chemical stability. We managed to control parenteral N-acetylcysteine stability, and to study the influence of additives on the decrease of N-acetylcysteine degradation. First, an HPLC-UV do...