Stability Study of Parenteral N-Acetylcysteine, and Chemical Inhibition of Its Dimerization

• Egile Nagusiak: Nicolas Primas (Egilea), Guillaume Lano (Egilea), Damien Brun (Egilea), Christophe Curti (Egilea), Marion Sallée (Egilea), Emmanuelle Sampol-Manos (Egilea), Edouard Lamy (Egilea), Charleric Bornet (Egilea), Stéphane Burtey (Egilea), Patrice Vanelle (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Parenteral N-acetylcysteine has a wide variety of clinical applications, but its use can be limited by a poor chemical stability. We managed to control parenteral N-acetylcysteine stability, and to study the influence of additives on the decrease of N-acetylcysteine degradation. First, an HPLC-UV do...