Targeting MetaLnc9/miR-143/FSCN1 axis inhibits oxidative stress and myofibroblast transdifferentiation in oral submucous fibrosis

• Main Authors: Ming-Yi Lu (Author), Pei-Ling Hsieh (Author), Shih-Chi Chao (Author), Chih-Yuan Fang (Author), Yoichi Ohiro (Author), Yi-Wen Liao (Author), Cheng-Chia Yu (Author), Min-Te Chang (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Persistent activation of myofibroblasts is attributed to various dysregulated biological events conferring multiple types of fibrosis diseases, including oral submucous fibrosis (OSF). Although the significance of non-coding RNAs (ncRNAs) in the occurrence of fibrosis has been ap...