Pharmacomodulations around an anti-Alzheimer drug-candidate

• Main Authors: Sylvain Marc (Author), Christophe Mésangeau (Author), Mathilde Coevoet (Author), Amélie Barczyk (Author), Stéphane Burlet (Author), Philippe Verwaerde (Author), Cecilia Estrella (Author), Cyrille Brantis (Author), Nicolas Sergeant (Author), Pascal Carato (Author), Patricia Melnyk (Author)
• 格式: 图书
• 出版: Elsevier, 2022-04-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Alzheimer's disease is a complex and multifactorial disease characterized by extracellular Aβ peptide deposits related to the deregulation of APP metabolism, intracellular aggregation of hyper and abnormally phosphorylated isoforms of Tau proteins, cell death and neuroinflammation. Targeting al...