External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort

Objective: To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods: Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that containe...

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Main Authors: Marije Lamain-de Ruiter (Author), Anneke Kwee (Author), Christiana A. Naaktgeboren (Author), Rebecca D. Louhanepessy (Author), Inge De Groot (Author), Inge M. Evers (Author), Floris Groenendaal (Author), Yolanda R. Hering (Author), Anjoke J. M. Huisjes (Author), Cornel Kirpestein (Author), Wilma M. Monincx (Author), Peter C. J. I. Schielen (Author), Annewil Van 'T Zelfde (Author), Charlotte M. Van Oirschot (Author), Simone A. Vankan-Buitelaar (Author), Mariska A. A. W. Vonk (Author), Therese A. Wiegers (Author), Joost J. Zwart (Author), Karel G. M. Moons (Author), Arie Franx (Author), Maria P. H. Koster (Author)
Format: Book
Published: Taylor & Francis Group, 2019-04-01T00:00:00Z.
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100 1 0 |a Marije Lamain-de Ruiter  |e author 
700 1 0 |a Anneke Kwee  |e author 
700 1 0 |a Christiana A. Naaktgeboren  |e author 
700 1 0 |a Rebecca D. Louhanepessy  |e author 
700 1 0 |a Inge De Groot  |e author 
700 1 0 |a Inge M. Evers  |e author 
700 1 0 |a Floris Groenendaal  |e author 
700 1 0 |a Yolanda R. Hering  |e author 
700 1 0 |a Anjoke J. M. Huisjes  |e author 
700 1 0 |a Cornel Kirpestein  |e author 
700 1 0 |a Wilma M. Monincx  |e author 
700 1 0 |a Peter C. J. I. Schielen  |e author 
700 1 0 |a Annewil Van 'T Zelfde  |e author 
700 1 0 |a Charlotte M. Van Oirschot  |e author 
700 1 0 |a Simone A. Vankan-Buitelaar  |e author 
700 1 0 |a Mariska A. A. W. Vonk  |e author 
700 1 0 |a Therese A. Wiegers  |e author 
700 1 0 |a Joost J. Zwart  |e author 
700 1 0 |a Karel G. M. Moons  |e author 
700 1 0 |a Arie Franx  |e author 
700 1 0 |a Maria P. H. Koster  |e author 
245 0 0 |a External validation of prognostic models for preeclampsia in a Dutch multicenter prospective cohort 
260 |b Taylor & Francis Group,   |c 2019-04-01T00:00:00Z. 
500 |a 1064-1955 
500 |a 1525-6065 
500 |a 10.1080/10641955.2019.1584210 
520 |a Objective: To perform an external validation of all published prognostic models for first-trimester prediction of the risk of developing preeclampsia (PE). Methods: Women <14 weeks of pregnancy were recruited in the Netherlands. All systematically identified prognostic models for PE that contained predictors commonly available were eligible for external validation. Results: 3,736 women were included; 87 (2.3%) developed PE. Calibration was poor due to overestimation. Discrimination of 9 models for LO-PE ranged from 0.58 to 0.71 and of 9 models for all PE from 0.55 to 0.75. Conclusion: Only a few easily applicable prognostic models for all PE showed discrimination above 0.70, which is considered an acceptable performance. 
546 |a EN 
690 |a first trimester 
690 |a preeclampsia 
690 |a external validation 
690 |a prognostic model 
690 |a Gynecology and obstetrics 
690 |a RG1-991 
655 7 |a article  |2 local 
786 0 |n Hypertension in Pregnancy, Vol 38, Iss 2, Pp 78-88 (2019) 
787 0 |n http://dx.doi.org/10.1080/10641955.2019.1584210 
787 0 |n https://doaj.org/toc/1064-1955 
787 0 |n https://doaj.org/toc/1525-6065 
856 4 1 |u https://doaj.org/article/d04ec5979843430e828cadb4f2d1cbe4  |z Connect to this object online.