DCR2, a Cellular Senescent Molecule, Is a Novel Marker for Assessing Tubulointerstitial Fibrosis in Patients with Immunoglobulin A Nephropathy

• Main Authors: Jia Chen (Author), Wei Hu (Author), Fei Xiao (Author), Lirong Lin (Author), Kehong Chen (Author), Liming Wang (Author), Xiaoyue Wang (Author), Yani He (Author)
• Format: Book
• Published: Karger Publishers, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Stress-induced cell senescence, which contributes to cell cycle arrest and is independent of age, plays an important role in chronic kidney disease (CKD) progression. DcR2, as a senescent marker, exclusively expressed in senescent tubular epithelia. The objective of this study was t...