The impact of phosphodiesterase‐5 inhibition or angiotensin‐converting enzyme inhibition on right and left ventricular remodeling in heart failure due to chronic volume overload

• Main Authors: Tereza Tykvartova (Author), Matus Miklovic (Author), Martin Kotrc (Author), Petra Skaroupkova (Author), Ludmila Kazdova (Author), Jaroslava Trnovska (Author), Vojtech Skop (Author), Michal Kolar (Author), Jiri Novotny (Author), Vojtech Melenovsky (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract While phosphodiesterase‐5 inhibition (PED5i) may prevent hypertrophy and failure in pressure‐overloaded heart in an experimental model, the impact of PDE5i on volume‐overload (VO)‐induced hypertrophy is unknown. It is also unclear whether the hypertrophied right ventricle (RV) and left vent...