IgA Enhances IGF-1 Mitogenic Activity Via Receptor Modulation in Glomerular Mesangial Cells: Implications for IgA-Induced Nephropathy

Background/Aim: Glomerulonephritis due to mesangial proliferation is responsible for renal dysfunction in IgA nephropathy (IgAN), however molecular mechanisms of pathogenesis are not well known. We examined the effect of IgA on Insulin-like Growth Factor-1 (IGF-1) activity, a potent mitogen with vit...

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Bibliographic Details
Main Authors: Amal Al-Eisa (Author), Gursev S. Dhaunsi (Author)
Format: Book
Published: Karger Publishers, 2017-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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